Full List - Dr. El Majdoubi

Publications:

  • M. El Majdoubi, O. Bar-Ilan, S. Batres, M. Kolipinski, L. Lima, D.C. Martinez and E. Romero: Effects of decreased gonadotropin-releasing hormone neuronal activity on fertility and adiposity in male GPR-4 rat. Frontiers in Neuroendocrinology 2006, 27, 78-79.
  • F Gomez, S.E. la Fleur, R.I. Weiner, M.F. Dallman and M. El Majdoubi (2005). Decreased gonadotropin-releasing hormone neuronal activity is associated with decreased fertility and dysregulation of food intake in the female GPR-4 transgenic rat. Endocrinology, 146:3800-3808
  • P.S. Tsai, S.M. Moenter, H.R. Postigo, M. El Majdoubi, T.R. Pak, J.C. Gill, S. Paruthiyil, S Werner and R.I. Weiner (2005). Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population. Molecular Endocrinology, 19:225-236.
  • M. El Majdoubi, S. Paruthiyil and R.I. Weiner (2003). Pulsatile luteinizing hormone and follicle-stimulating hormone secretion and gonadotropin subunit mRNA levels in the ovariectomized GPR-4 transgenic rat. Neuroendocrinology, 78:287-293.
  • S. Paruthiyil, M. El Majdoubi,* M. Conti and R.I. Weiner (2002). Phosphodiesterase expression targeted to gonadotropin-releasing hormone neurons inhibits luteinizing hormone pulses in transgenic rats. Proceedings of the National Academy of Science, USA, 99: 17191-17196. * Co-first author
  • M. El Majdoubi and R.I. Weiner (2002). Localization of olfactory cyclic nucleotide-gated channels in rat gonadotropin-releasing hormone neurons. Endocrinology, 143:2441-2444.
  • M. El Majdoubi, A. Sahu and T.M. Plant (2000). Changes in hypothalamic gene expression associated with the arrest of pulsatile gonadotropin-releasing hormone release during infancy in the agonadal male rhesus monkey. Endocrinology, 141:3273-3277.
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (2000). Activity-dependent morphological synaptic plasticity in an adult neurosecretory system: Magnocellular oxytocin neurons of the hypothalamus. Biochemistry and Cell Biology, 78:317-327.
  • M. El Majdoubi, A. Sahu, S. Ramaswamy and T.M. Plant (2000). Neuropeptide Y: A hypothalamic brake restraining the onset of puberty in primates. Proceedings of the National Academy of Science, USA, 97:6179-6184.
  • M. El Majdoubi, S. Ramaswamy, A. Sahu and T.M. Plant (2000). Effects of orchidectormy on levels of the messenger ribonucleic acids (mRNAs) encoding Gonadotropin-Releasing Hormone and other hypothalamic peptides in the adult male rhesus monkey (Macaca mulatta). Journal of Neuroendocrinology, 12:167-176.
  • T. M. Plant, M. El Majdoubi, A.R. Durrant and A. Sahu (1999). Development and organization of the hypophysiotropic hypothalamus driving the pituitary-gonadal axis in the rhesus monkey. Annales d’Endocrinologie (Paris), 60:60–66.
  • M. El Majdoubi, A. Sahu and T.M. Plant (1998). Effect of estrogen on hypothalamic Transforming Growth Factor alpha (TGF?) and Gonadotropin-Releasing Hormone (GnRH) gene expression in the female rhesus monkey. Neuroendocrinology, 67:228–235.
  • D.T. Theodosis, M. El. Majdoubi, K. Pierre and D.A. Poulain (1998). Factors governing activity–dependent structural plasticity of the hypothalamo-neurohypophysial system. Cellular and Molecular Neurobiology, 18:283–296.
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (1997). Lactation-induced plasticity of the supraoptic nucleus augments axo-dendritic and axo-somatic GABAergic and glutamatergic synapses: An ultrastructural analysis using the disector method. Neuroscience, 80:1137–1147.
  • E.H. Michaloudi, M. El Majdoubi,  D.A. Poulain, G.H. Papadopoulos and D.T. Theodosis (1997). The noradrenegic innervation of identified hypothalamic magnocellular somata and its contribution to lactation-induced plasticity.  Journal of Neuroendocrinology, 9:17–23.
  • M. El Majdoubi,  M.H. Metz–Boutigue, P. Garcia-Sablonne, D.T. Theodosis and D. Aunis (1996).  Immunocytochemical localization of chromogranin A in the normal and stimulated hypothalamo-neurohypophysial system of the rat. Journal of Neurocytology, 25:405-416.
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (1996). The glutamatergic innervation of Oxytocin- and vasopressin-secreting neurons in the rat supraoptic nucleus and its contribution to lactation-induced synaptic plasticity.  European Journal of Neuroscience, 8:1377-1389.
  • D.T. Theodosis, M. El Majdoubi, U. Gies and D.A. Poulain (1995).  Physiologically-linked structural plasticity of inhibitory and excitatory synaptic inputs to oxytocinergic neurons. Advances in Experimental Medicine and Biology, 395:155-171.


Abstracts:

  • F Gomez, SE la Fleur, M. El Majdoubi, S Manalo, R.I. Weiner and MF Dallman (2003). Female GPR-4 transgenic rats on high caloric diet: a model of abdominal obesity and hyperandrogenism. 85th Annual Meeting of the Endocrine Society, Philadelphia, PA, June 19-22. (Abstract P3-46)
  • M. El Majdoubi, F Gomez, SE la Fleur, S Manalo, SH Mellon, MF Dallman and R.I. Weiner (2003). Age-related development of anovulation and cystic ovarian follicles in GPR-4 transgenic rats. 85th Annual Meeting of the Endocrine Society, Philadelphia, PA, June 19-22. (Abstract P3-45)
  • M. El Majdoubi, S. Paruthiyil and R.I. Weiner (2002). Targeting of the expression of phosphodiesterase 4D1 (PDE4D1) to GnRH neurons in transgenic female rats inhibits the pulsatile release of LH and estrous cyclicity. 84th Annual Meeting of the Endocrine Society, San Francisco, CA, June 19-22. (Abstract OR45-6)
  • M. El Majdoubi, M. F. Dallman and R. I. Weiner (2001).  Localization of olfactory cyclic nucleotide-gated channels in rat GnRH neurons. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA, November 10-15. (Abstract 466.5)
  • S. Paruthiyil, M. El Majdoubi, P. Butler, F. Gomez Oliver, J. L. Roberts and R. I. Weiner (2001).  Genetic targeting of GnRH neurons in transgenic rats. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA, November 10-15. (Abstract 734.2)
  • M. Arslan, M. El Majdoubi, S. Ramaswamy, A. Sahu and T.M. Plant (2000). Neuropeptide Y regulation of growth hormone secretion prior to the onset of puberty in the male rhesus monkey. 82nd Annual Meeting of the Endocrine Society, Calgary, Canada, June 21-24. (Abstract 658)
  • M. El Majdoubi (1999). Activity-dependent morphological synaptic plasticity in the adult hypothalamus. 5th International Congress of Comparative Physiology and Biochemistry, Calgary, Canada, August 23-28. Comparative Physiology and Biochemistry, 124A, S12.
  • M. El Majdoubi, A. Sahu, S. Ramawasmy and T.M. Plant (1999). Further evidence for the view that NPY is  major component of the prepubertal brake on pulsatile GnRH release in the male monkey. 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FL, October 23-28. (Abstract 320.1)
  • T.M. Plant, M. El Majdoubi, A. Sahu and S. Ramaswamy (1999). Hypothalamic gene expression during puberty in the monkey. 81st Annual Meeting of the Endocrine Society, San Diego, CA, June 12-15. (Abstract 320.1)
  • M. El Majdoubi, A. Sahu and T.M. Plant (1999).  The decrease in the hypophysiotropic drive to the pituitary-gonadal axis in late infancy is associated with an increase in hypothalamic levels of the mRNA encoding NPY in the male rhesus monkey. 81st Annual Meeting of the Endocrine Society, San Diego, CA, June 12-15. (Abstract OR31-4)
  • M. El Majdoubi, A. Sahu and T.M. Plant (1998). Pubertal changes in hypothalamic GnRH and related peptide gene expression in the monkey.  28th Annual Meeting of the Society for Neuroscience, Los Angeles, CA, November 7-12. (Abstract 110.6)
  • M. El Majdoubi, S. Ramaswamy, A. Sahu and T.M. Plant (1998). The negative feedback control of LH by testosterone in the male rhesus monkey is mediated, in part, by suppression of GnRH gene expression. 4th International Congress of Neuroendocrinology, Kitakyushu, Japan, October 11-16. Neuroendocrinology, 74 (2), 473.
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (1996).  Analysis of plasticity of GABAergic and glutamatergic inputs to hypothalamic neurons by the disector method. 2nd Meeting of European Neuroscience, Strasbourg, France, September 24-28. European Journal of Neuroscience, 9, 34.


Presentations:

  • F Gomez, SE la Fleur, M. El Majdoubi, S Manalo, R.I. Weiner and MF Dallman (2003). Female GPR-4 transgenic rats on high caloric diet: a model of abdominal obesity and hyperandrogenism. 85th Annual Meeting of the Endocrine Society, Philadelphia, PA, June 19-22. (poster)
  • M. El Majdoubi, F Gomez, SE la Fleur, S Manalo, SH Mellon, MF Dallman and R.I. Weiner (2003). Age-related development of anovulation and cystic ovarian follicles in GPR-4 transgenic rats. 85th Annual Meeting of the Endocrine Society, Philadelphia, PA, June 19-22. (poster)
  • M. El Majdoubi, S. Paruthiyil and R.I. Weiner (2002). Targeting of the expression of phosphodiesterase 4D1 (PDE4D1) to GnRH neurons in transgenic female rats inhibits the pulsatile release of LH and estrous cyclicity. 84th Annual Meeting of the Endocrine Society, San Francisco, CA, June 19-22. (oral communication)
  • M. El Majdoubi, M. F. Dallman and R. I. Weiner (2001).  Localization of olfactory cyclic nucleotide-gated channels in rat GnRH neurons. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA, November 10-15. (oral communication)
  • S. Paruthiyil, M. El Majdoubi, P. Butler, F. Gomez Oliver, J. L. Roberts and R. I. Weiner (2001).  Genetic targeting of GnRH neurons in transgenic rats. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA, November 10-15. (poster)
  • M. El Majdoubi, A. Sahu, S. Ramaswamy and T.M. Plant (1999). Further evidence for the view that NPY is a major component of the prepubertal brake on pulsatile GnRH release in the male monkey. 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FL, October 23-28. (oral communication)
  • M. El Majdoubi (1999). Activity-dependent structural synaptic plasticity in the adult hypothalamus. 5th Intl Congress of Comparative Physiology and Biochemistry, Calgary, Canada, August 23-28. (invited speaker)
  • M. El Majdoubi, A. Sahu and T.M. Plant (1999).  The decrease in the hypophysiotropic drive to the pituitary-gonadal axis in late infancy is associated with an increase in hypothalamic levels of the mRNA encoding NPY in the male rhesus monkey. 81st Annual Meeting of the Endocrine Society, San Diego, CA, June 12-15. (oral communication)
  • T.M. Plant, M. El Majdoubi, A. Sahu and S. Ramaswamy (1999). Hypothalamic gene expression during puberty in the monkey. 81st Annual Meeting of the Endocrine Society, San Diego, CA, June 12-15. (oral communication)
  • M. El Majdoubi, A. Sahu and T.M. Plant (1998). Pubertal changes in hypothalamic GnRH and related peptide gene expression in the monkey. 28th Annual meeting of the Society for Neuroscience, Los Angeles, CA, November 7-12. (oral communication)
  • M. El Majdoubi, S. Ramaswamy, A. Sahu and T.M. Plant (1998).  Effects of orchidectomy on GnRH and related peptide gene expression in the adult male rhesus monkey. 4th International Congress of Neuroendocrinology, Kitakyushu, Japan, October 11-16. (poster)
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (1996). Analysis of plasticity of GABAergic and glutamatergic inputs to hypothalamic neurons by the 'disector' method.  2nd Meeting of European Neuroscience, Strasbourg, September 24-28. (oral communication)
  • M. El Majdoubi, D.A. Poulain and D.T. Theodosis (1995).  The glutamatergic innervation of oxytocin and vasopressin neurons in the rat supraoptic nucleus and its contribution to lactation-induced synaptic plasticity: An ultrastructural immunocytochemical analysis. 2nd Intl Conference of the Society of Neuroscientists of Africa, Marrakech, Morocco, April 17-21. (invited speaker)
  • D.T. Theodosis, M. El Majdoubi, U. Gies, D.A. Poulain (1995).  Structural plasticity of inhibitory and excitatory synaptic inputs to oxytocin neurons. OXYTOCIN - Cellular and Molecular Approches in Medecine and Research, Humburg, Germany, April 30 – May 4. (oral communication)